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FEATURES

DESCRIPTION

Also known as MAN1_HUMAN, LEMD3, MAN1. Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest. Interacts with SMAD1, SMAD2, SMAD3 and SMAD5. Binds to both phosphorylated and unphosphorylated R-SMADS.

Also known as MAN1_HUMAN, LEMD3, MAN1. Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced c ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LEMD3

Inner nuclear membrane protein Man1

Molecular Synopsis

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