FEATURES

FAMILY

DESCRIPTION

Also known as RTCB_HUMAN, RTCB, C22orf28. Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3', 5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. Catalytic component of the tRNA-splicing ligase complex.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RTCB

RNA-splicing ligase RtcB homolog

RTCB

Molecular Synopsis