FEATURES

DESCRIPTION

Also known as EMIL1_HUMAN, EMILIN1, EMI. May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quaternary assembly to higher-order polymers via intermolecular disulfide bonds. Interacts with EMILIN2. Interacts with EFEMP2; this interaction promotes the incorporation of EFEMP2 into the extracellular matrix (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EMILIN1

Mutations

Mutation(s) distribution

Mutations table