FEATURES

FAMILY

cation diffusion facilitator (CDF) transporter (TC 2.A.4) family

DESCRIPTION

Also known as MAMM_MAGGM, mamM. Essential for magnetosome formation; required for stable accumulation of MamB (PubMed:22007638). May nucleate iron crystal formation (Probable). Probably binds and transports iron. Binds divalent cations, possibly up to 3 Zn(2+) per dimer in vitro, probably iron in vivo (Probable) (PubMed:30811856). One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis (PubMed:27286560). Forms homodimers via its C-terminal domain (CTD) in the presence of metal cations (Probable). Interacts with MamB via their CTD (PubMed:22007638, PubMed:29243866) (Probable). Isolated CTD forms homodimers (PubMed:24658343, PubMed:24819161, PubMed:27550551, PubMed:30811856).

EXTERNAL LINKS

mamM

Magnetosome protein MamM

mamM

Molecular Synopsis