4FAO

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FAO_1

Bioassembly 4FAO_2

Bioassembly 4FAO_3

Bioassembly 4FAO_4

Bioassembly 4FAO_5

Bioassembly 4FAO_6

Chain 4FAO_A

Chain 4FAO_B

Chain 4FAO_C

Chain 4FAO_D

Chain 4FAO_E

Chain 4FAO_F

Chain 4FAO_G

Chain 4FAO_H

Chain 4FAO_I

Chain 4FAO_J

Chain 4FAO_K

Chain 4FAO_L

Chain 4FAO_M

Chain 4FAO_N

Chain 4FAO_O

Chain 4FAO_P

Chain 4FAO_Q

Chain 4FAO_R

Chain 4FAO_S

Chain 4FAO_T

Chain 4FAO_U

Chain 4FAO_V

Chain 4FAO_W

Chain 4FAO_X

Chain 4FAO_a

Chain 4FAO_b

Chain 4FAO_c

Chain 4FAO_d

Chain 4FAO_e

Chain 4FAO_f

Chain 4FAO_g

Chain 4FAO_h

Chain 4FAO_i

Chain 4FAO_j

Chain 4FAO_k

Chain 4FAO_l

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GENERAL

TITLE

SPECIFICITY AND STRUCTURE OF A HIGH AFFINITY ACTIVIN-LIKE 1 (ALK1) SIGNALING COMPLEX

DATE LAST MODIFIED

29 Jul 2020

RELEASE

20 Jun 2012

OBSOLETE

CLASSIFICATION

SIGNALING PROTEIN/SIGNALING PROTEIN

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 31 1 2

RESOLUTION RANGE HIGH

3.35

RESOLUTION RANGE LOW

PUBMED ID

22718755

DOI

10.1074/JBC.M112.377960

PDBe

LIGANDS

49551 , 2694652

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q9UK05	BMP9, GDF2	CRICETULUS GRISEUS	HUMAN	GDF-2, BONE MORPHOGENETIC PROTEIN 9, BMP-9	Mutations
Q5U5Q3	BMP9, GDF2	CRICETULUS GRISEUS	HUMAN	GDF-2, BONE MORPHOGENETIC PROTEIN 9, BMP-9
P48643	ACVRL1, ACVRLK1, ALK1	CRICETULUS GRISEUS	HUMAN	SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
P37023	ACVRL1, ACVRLK1, ALK1	CRICETULUS GRISEUS	HUMAN	SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...	Mutations
P55735	ACTRIIB, ACVR2B	CRICETULUS GRISEUS	HUMAN	ACTIVIN RECEPTOR TYPE IIB, ACTR-IIB
Q5U5Q3	ACTRIIB, ACVR2B	CRICETULUS GRISEUS	HUMAN	ACTIVIN RECEPTOR TYPE IIB, ACTR-IIB
Q5U5Q3	BMP9, GDF2	CRICETULUS GRISEUS	HUMAN	GDF-2, BONE MORPHOGENETIC PROTEIN 9, BMP-9
Q5U5Q3	BMP9, GDF2	CRICETULUS GRISEUS	HUMAN	GDF-2, BONE MORPHOGENETIC PROTEIN 9, BMP-9
P40227	ACVRL1, ACVRLK1, ALK1	CRICETULUS GRISEUS	HUMAN	SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...
P0C6U3-Nsp5	ACVRL1, ACVRLK1, ALK1	CRICETULUS GRISEUS	HUMAN	SKR3, ACTIVIN RECEPTOR-LIKE KINASE 1, ALK-1, TGF-B ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402