5L01

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5L01_A

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GENERAL

TITLE

TRYPTOPHAN 5-HYDROXYLASE IN COMPLEX WITH INHIBITOR (3~{S})-8-[2- AZANYL-6-[(1~{R})-1-(4-CHLORANYL-2-PHENYL-PHENYL)-2,2,2- TRIS(FLUORANYL)ETHOXY]PYRIMIDIN-4-YL]-2,8-DIAZASPIRO[4.5]DECANE-3- CARBOXYLIC ACID

DATE LAST MODIFIED

RELEASE

25 Jan 2017

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

PUBMED ID

28041831

DOI

10.1016/J.BMCL.2016.12.053

PDBe

5L01

LIGANDS

809062 , 2692985

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P17752	TPH1, TPH, TPRH, TRPH	ESCHERICHIA COLI K-12	HUMAN	TRYPTOPHAN 5-MONOOXYGENASE 1	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402