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5L01

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GENERAL
TITLE
TRYPTOPHAN 5-HYDROXYLASE IN COMPLEX WITH INHIBITOR (3~{S})-8-[2- AZANYL-6-[(1~{R})-1-(4-CHLORANYL-2-PHENYL-PHENYL)-2,2,2- TRIS(FLUORANYL)ETHOXY]PYRIMIDIN-4-YL]-2,8-DIAZASPIRO[4.5]DECANE-3- CARBOXYLIC ACID
DATE LAST MODIFIED
-
RELEASE
25 Jan 2017
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2016.12.053

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P17752 TPH1, TPH, TPRH, TRPH ESCHERICHIA COLI K-12 HUMAN TRYPTOPHAN 5-MONOOXYGENASE 1 HUMAN
TRYPTOPHAN 5-MONOOXYGENASE 1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402