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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE IN COMPLEX WITH (3R,4S)-1-((4-AMINO-5H-PYRROLO[3,2- D]PYRIMIDIN-7-YL)METHYL)-4-(((3-(1-BUTYL-1H-1,2,3-TRIAZOL-4-YL) PROPYL)THIO)METHYL)PYRROLIDIN-3-OL
DATE LAST MODIFIED
4 Dec 2019
RELEASE
20 Mar 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
1.91
RESOLUTION RANGE LOW
79.43
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01642
PDBe
6DZ3
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q13126 | MTAP, MSAP | ESCHERICHIA COLI | HUMAN | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, MTAPASE | Mutations | |
| P62273 | MTAP, MSAP | ESCHERICHIA COLI | HUMAN | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, MTAPASE | ||
| P08708 | MTAP, MSAP | ESCHERICHIA COLI | HUMAN | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, MTAPASE |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402