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GENERAL
TITLE
CRYSTAL STRUCTURE OF STABILIZED ACTIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1-W175F) IN COMPLEX WITH TWO INHIBITORY NANOBODIES (VHH-2G-42, VHH-2W-64)
DATE LAST MODIFIED
11 Mar 2020
RELEASE
1 Jan 2020
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.96
RESOLUTION RANGE LOW
94.97
PUBMED ID
DOI
10.1111/JTH.14716
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P05121 SERPINE1, PAI1, PLANH1 ESCHERICHIA COLI BL21(DE3) HUMAN PAI-1,ENDOTHELIAL PLASMINOGEN ACTIVATOR INHIBITOR,SERPIN E1 HUMAN
PAI-1,ENDOTHELIAL PLASMINOGEN ACTIVATOR INHIBITOR, ...
Mutations
-- ESCHERICHIA COLI BL21(DE3) ALPACA -- ALPACA --
-- ESCHERICHIA COLI BL21(DE3) ALPACA -- ALPACA --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402