6NFZ

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6NFZ_1

Chain 6NFZ_A

Chain 6NFZ_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF DIPHOSPHORYLATED HPK1 KINASE DOMAIN IN COMPLEX WITH SUNITINIB IN THE ACTIVE STATE.

DATE LAST MODIFIED

26 Jun 2019

RELEASE

1 May 2019

OBSOLETE

CLASSIFICATION

SIGNALING PROTEIN

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

H 3 2

RESOLUTION RANGE HIGH

2.966

RESOLUTION RANGE LOW

99.995

PUBMED ID

DOI

10.1074/JBC.AC119.007466

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	A0A024B7W1	MAP4K1, HPK1	SPODOPTERA FRUGIPERDA	HUMAN	HEMATOPOIETIC PROGENITOR KINASE,MAPK/ERK KINASE KI ...
	Q92918	MAP4K1, HPK1	SPODOPTERA FRUGIPERDA	HUMAN	HEMATOPOIETIC PROGENITOR KINASE,MAPK/ERK KINASE KI ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402