FEATURES

FAMILY

DESCRIPTION

Also known as AA2AR_HUMAN, ADORA2A, ADORA2. Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Interacts (via cytoplasmic C-terminal domain) with USP4; the interaction is direct (PubMed:16339847). May interact with DRD4 (PubMed:18832607). Interacts with NECAB2 (PubMed:17689978). Interacts (via cytoplasmic C-terminal domain) with GAS2L2; interaction enhances receptor-mediated adenylyl cyclase activity (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ADORA2A

Mutations

Mutation(s) distribution

Mutations table