FEATURES

FAMILY

DESCRIPTION

Also known as CCKAR_HUMAN, CCKAR, CCKRA. Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CCKAR

Cholecystokinin receptor type A

CCKAR

Molecular Synopsis