FEATURES

FAMILY

DESCRIPTION

Also known as GASR_HUMAN, CCKBR, CCKRB. Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system., Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.

Also known as GASR_HUMAN, CCKBR, CCKRB. Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CCKBR

Gastrin/cholecystokinin type B receptor

CCKBR

Molecular Synopsis