FEATURES

FAMILY

DESCRIPTION

Also known as MTR1B_HUMAN, MTNR1B. High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Interacts with GPR61, GPR62 and GPR135 (PubMed:28827538).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MTNR1B

Melatonin receptor type 1B

MTNR1B

Molecular Synopsis