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FAMILY

G-protein coupled receptor 1 family

DESCRIPTION

Also known as GPBAR_HUMAN, GPBAR1, TGR5. Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.

Also known as GPBAR_HUMAN, GPBAR1, TGR5. Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GPBAR1

G-protein coupled bile acid receptor 1

Mutations

Mutation(s) distribution

Mutations table

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